Proteogenix

Proteogenix: Your One-Stop Shop for Antibody Production and Development Services

Proteogenix is a leading antibody production company that offers a wide range of gene and peptide synthesis, protein production, and antibody development services. With over 1500+ antibody generations under their belt, Proteogenix has established itself as a trusted partner for researchers, scientists, and biotech companies worldwide.

At Proteogenix, the team of experts is dedicated to providing high-quality products and services that meet the unique needs of each client. Whether you need custom antibodies for research or therapeutic purposes, Proteogenix has the expertise to deliver results that exceed your expectations.

Gene Synthesis Services

Proteogenix offers gene synthesis services that enable researchers to create custom DNA sequences with high accuracy and efficiency. The company uses state-of-the-art technology to synthesize genes up to 20 kb in length with fast turnaround times. The team at Proteogenix can also optimize gene sequences for expression in various host systems such as bacteria, yeast, insect cells or mammalian cells.

Peptide Synthesis Services

Proteins are made up of amino acids linked together by peptide bonds. Peptides are short chains of amino acids (less than 50) which can be used as antigens or mimotopes in immunization protocols or as probes in biochemical assays. At Proteogenix we offer peptide synthesis services using solid-phase chemistry on automated synthesizers from small scale (mg) up to large scale (g). We also provide modifications such as phosphorylation or biotinylation on specific residues.

Protein Production Services

The team at Proteogenix has extensive experience in producing recombinant proteins using various expression systems including bacterial (E.coli), yeast (Pichia pastoris), insect cells (baculovirus) or mammalian cells (CHO). We offer different purification strategies depending on the protein properties such as affinity chromatography, ion exchange chromatography or size exclusion chromatography. We also provide protein labeling services such as fluorescent dyes or biotin.

Antibody Development Services

Proteogenix offers a comprehensive range of antibody development services including polyclonal and monoclonal antibody production, hybridoma generation, phage display technology and recombinant antibody engineering. Our team of experts can help you select the best strategy for your project based on your specific needs and budget.

Polyclonal Antibody Production

Polyclonal antibodies are produced by immunizing animals (such as rabbits, goats or sheep) with an antigen. The animal's immune system will produce a mixture of antibodies that recognize different epitopes on the antigen. Proteogenix offers custom polyclonal antibody production services using various host species depending on the client's requirements.

Monoclonal Antibody Production

Monoclonal antibodies are produced by immortalizing B cells that produce a single type of antibody against an antigen. This results in highly specific antibodies that can be used for various applications such as diagnostics or therapeutics. Proteogenix offers custom monoclonal antibody production services using hybridoma technology or phage display technology.

Hybridoma Generation

Hybridomas are created by fusing B cells from immunized animals with myeloma cells to create immortalized cell lines that produce monoclonal antibodies against an antigen. Proteogenix has extensive experience in generating hybridomas using various fusion protocols and screening strategies to obtain high-affinity clones.

Phage Display Technology

Phage display is a powerful technique for selecting high-affinity binding peptides or proteins from large libraries displayed on bacteriophages (viruses that infect bacteria). Proteogenix offers phage display library construction and screening services to identify peptides/proteins with desired properties such as specificity, affinity, stability etc.

Recombinant Antibody Engineering

Recombinant DNA technology allows the engineering of antibodies with desired properties such as increased affinity, specificity or stability. Proteogenix offers custom antibody engineering services using various strategies such as site-directed mutagenesis, antibody humanization or bispecific antibody generation.

Conclusion

Proteogenix is a leading provider of gene and peptide synthesis, protein production and antibody development services. With over 1500+ antibody generations under their belt, Proteogenix has established itself as a trusted partner for researchers, scientists and biotech companies worldwide. The team at Proteogenix is dedicated to providing high-quality products and services that meet the unique needs of each client. Whether you need custom antibodies for research or therapeutic purposes, Proteogenix has the expertise to deliver results that exceed your expectations. Contact us today to learn more about our services!