About Seracare life sciences
SeraCare Life Sciences: Revolutionizing Quality Control Tools for NGS Clinical Laboratories and IVD Assay Development
SeraCare Life Sciences is a leading provider of quality control tools for next-generation sequencing (NGS) clinical laboratories and in vitro diagnostic (IVD) assay development. The company offers custom reference materials, controls, and reagents for NGS, molecular and serology, biological materials, and reagents.
With over 30 years of experience in the industry, SeraCare has established itself as a trusted partner to clinical laboratories worldwide. The company's mission is to enable precision medicine by providing reliable quality control solutions that ensure accurate test results.
Quality Control Tools for NGS Clinical Laboratories
NGS technology has revolutionized the field of genomics by enabling researchers to sequence entire genomes at an unprecedented speed and cost. However, the accuracy of NGS-based tests depends on several factors such as sample preparation, library construction, sequencing chemistry, bioinformatics analysis pipeline among others. Any errors or variations in these steps can lead to inaccurate test results which can have serious consequences for patients.
To address this challenge SeraCare offers a range of quality control tools that help clinical laboratories validate their assays with confidence. These include:
1. AccuSpan™ DNA Mix: A set of synthetic DNA fragments that mimic human genomic DNA with known variants at specific positions. This product enables labs to assess the accuracy and sensitivity of their variant calling pipelines.
2. Seraseq™ Tumor Mutation Mix-II: A set of synthetic DNA fragments that mimic tumor-derived DNA with known mutations at specific positions commonly found in cancer patients. This product enables labs to evaluate the performance of their cancer gene panels or exome sequencing assays.
3. iQ™ NGS QC Management Software: A cloud-based software platform that provides real-time monitoring and analysis of NGS data quality metrics such as read depth distribution, GC bias plot among others.
Custom Reference Materials for IVD Assay Development
In addition to its offerings for clinical laboratories SeraCare also provides custom reference materials for IVD assay development companies who are developing new diagnostic tests based on various technologies such as PCR/qPCR/RT-qPCR/NGS etc., These reference materials are critical components used during assay validation studies which demonstrate analytical performance characteristics such as limit-of-detection (LOD), limit-of-quantification (LOQ), linearity etc.,
Some examples include:
1.Seraseq™ Inherited Cancer Panel SNV Mix v2: A set of synthetic DNA fragments containing single nucleotide variants (SNVs) associated with inherited cancer syndromes such as BRCA1/BRCA2 mutations found in breast/ovarian cancer patients.
2.Seraseq™ Myeloid Mutation Mix v3: A set of synthetic DNA fragments containing mutations commonly found in myeloid malignancies such as acute myeloid leukemia(AML).
Biological Materials & Reagents
Apart from its core business areas mentioned above SeraCare also offers biological materials like plasma samples from healthy donors or disease state samples like HIV/HCV infected plasma samples etc., These products are used by researchers who need access to high-quality biological specimens during their research studies.
Conclusion
In conclusion,Seracare life sciences is an innovative company dedicated towards providing best-in-class Quality Control Tools not only limited towards Next Generation Sequencing but also catering towards other fields like Molecular Biology,Serology,Biological Materials & Reagents.Their products have been widely accepted globally due to its reliability ,accuracy & precision .Their commitment towards enabling Precision Medicine through reliable Quality Control Solutions makes them stand out amongst other competitors .