About Avid bioservices
Avid Bioservices is a leading drug substance and biologics contract manufacturing organization (CDMO) located in California. The company has extensive experience in process development, analytical services, CGMP clinical and commercial manufacturing, and viral vector services. Avid Bioservices is committed to providing high-quality services to its clients by leveraging its expertise in the field of biopharmaceuticals.
The company's state-of-the-art facilities are equipped with cutting-edge technology that enables it to provide a wide range of services to its clients. Avid Bioservices' team of experts includes scientists, engineers, and technicians who work together to ensure that each project is completed on time and within budget.
One of the key strengths of Avid Bioservices is its expertise in process development. The company has developed a proprietary platform for the production of recombinant proteins that allows for rapid optimization of protein expression levels. This platform has been used successfully for the production of a wide range of proteins including monoclonal antibodies, enzymes, growth factors, cytokines, and more.
In addition to process development, Avid Bioservices also offers analytical services such as method development and validation, stability testing, release testing, impurity analysis, and more. These services are critical for ensuring that products meet regulatory requirements before they can be approved for use.
Avid Bioservices' CGMP clinical manufacturing capabilities include cell culture production up to 2000L scale using single-use bioreactors or stainless steel vessels with perfusion or fed-batch processes; purification using chromatography techniques such as affinity chromatography; filtration technologies like ultrafiltration/diafiltration (UF/DF), nanofiltration (NF), microfiltration (MF); formulation & filling into vials or syringes under sterile conditions; lyophilization cycle optimization & execution; packaging & labeling according to client specifications.
The company's commercial manufacturing capabilities include large-scale cell culture production up to 20kL scale using single-use bioreactors or stainless steel vessels with perfusion or fed-batch processes; purification using chromatography techniques such as affinity chromatography; filtration technologies like ultrafiltration/diafiltration (UF/DF), nanofiltration (NF), microfiltration (MF); formulation & filling into vials or syringes under sterile conditions; lyophilization cycle optimization & execution; packaging & labeling according to client specifications.
Avid Bioservices also offers viral vector services which include upstream processing from transfection through harvest at small- through large-scale volumes up-to 2000L scale using single-use bioreactors or stainless steel vessels with perfusion or fed-batch processes followed by downstream processing including clarification via depth filtration followed by column-based purification steps utilizing ion exchange chromatography resins specific for viral vectors along with tangential flow filtration steps designed specifically for virus particles resulting in highly purified virus preparations suitable for preclinical studies through Phase III clinical trials
Overall Avid bioservice provides end-to-end solutions from early-stage process development all the way through commercial manufacture while maintaining quality standards throughout all stages which makes them stand out among other CDMOs.