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Formed in 2012, DeuteRx is a virtual biopharmaceutical company focused on improving racemic drugs for patients. Our team has pioneered the use of Deuterium-Enabled Chiral Switching (DECS) to isolate a single stereoisomer from a mixture of interconverting stereoisomers. This revolutionary strategy stabilizes the preferred stereoisomer in existing drugs sold as racemic mixtures to reduce deleterious side-effects and improve efficacy. We have applied DECS to a wide range of clinical therapies, including the deuterium-stabilized R-stereoisomer of pioglitazone for nonalcoholic steatohepatitis (NASH) (PXL065, acquired by Poxel in 2018) and the deuterium-stabilized S-stereoisomer of lenalidomide (DRX-053, acquired by Celgene in 2012).
US 300 brickstone square
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