About Gifford bioscience
Gifford Bioscience: Your Trusted Partner in Preclinical Contract Research
Gifford Bioscience is a leading preclinical contract research organization (CRO) that specializes in receptor pharmacology. With over 20 years of experience, Gifford Bioscience has established itself as a trusted partner for pharmaceutical and biotech companies seeking high-quality, reliable data to support their drug discovery and development programs.
At Gifford Bioscience, we understand the importance of accurate and timely data in drug development. Our team of experienced scientists is dedicated to providing our clients with the highest quality preclinical research services available. We specialize in ligand binding assays, receptor occupancy studies, autoradiography, and surface plasmon resonance (SPR) assays.
Our ligand binding assays are designed to measure the affinity and specificity of small molecules for their target receptors. We offer both radioligand binding assays using traditional scintillation counting methods as well as non-radioactive fluorescence-based assays using state-of-the-art microplate readers.
Receptor occupancy studies are used to determine the extent to which a drug occupies its target receptor at various doses or concentrations. This information is critical for understanding the pharmacokinetics and pharmacodynamics of a drug candidate.
Autoradiography is a powerful imaging technique that allows us to visualize the distribution of radiolabeled compounds within tissues or cells. This technique can be used to study receptor localization, density, and occupancy in vivo or ex vivo.
Finally, our SPR assays provide real-time measurements of molecular interactions between proteins or small molecules. This technology allows us to study protein-protein interactions as well as protein-ligand interactions with high sensitivity and specificity.
At Gifford Bioscience, we pride ourselves on our ability to deliver high-quality data on time and within budget. Our team works closely with each client throughout every stage of their project from experimental design through data analysis and interpretation.
In addition to our core services, we also offer a range of complementary services including cell culture, radiolabeling, and custom assay development. Our state-of-the-art facilities are equipped with the latest instrumentation and technology to ensure that we can meet the needs of even the most complex projects.
At Gifford Bioscience, we are committed to providing our clients with exceptional service and high-quality data. Contact us today to learn more about how we can help you advance your drug discovery and development programs.