About Advanced mammalian biomanufacturing innovation center (ambic)
Advanced Mammalian Biomanufacturing Innovation Center (AMBIC) is a research center that focuses on mammalian cell culture upstream development. It is the first Industry/University Cooperative Research Center (I/UCRC) dedicated to this field. The center aims to develop innovative technologies and processes for the biomanufacturing industry, with a focus on mammalian cells.
The biomanufacturing industry has been growing rapidly in recent years, driven by the increasing demand for biologics and biosimilars. These products are used in the treatment of various diseases such as cancer, autoimmune disorders, and infectious diseases. Mammalian cells are widely used in the production of these products due to their ability to produce complex proteins with post-translational modifications that are similar to those found in humans.
AMBIC's mission is to advance mammalian cell culture technology through collaborative research between academia and industry partners. The center brings together leading researchers from universities across the United States who specialize in different areas of mammalian cell culture upstream development. These researchers work closely with industry partners who provide funding and expertise to support research projects.
One of AMBIC's main goals is to develop new technologies that can improve the efficiency and productivity of mammalian cell culture processes while maintaining product quality. This includes developing new media formulations, optimizing process parameters such as temperature, pH, and agitation rate, and exploring new methods for cell line development.
Another important area of research at AMBIC is process analytical technology (PAT). PAT involves using real-time monitoring tools such as sensors and spectroscopy to monitor critical process parameters during manufacturing. This allows manufacturers to make real-time adjustments during production runs which can improve product quality while reducing costs.
AMBIC also places a strong emphasis on education and workforce development. The center offers training programs for graduate students who are interested in pursuing careers in biomanufacturing or related fields. These programs provide students with hands-on experience in mammalian cell culture upstream development and exposure to industry partners.
In addition to its research and education programs, AMBIC also provides a platform for networking and collaboration between academia and industry. The center hosts regular workshops, conferences, and symposia where researchers can share their latest findings with industry partners and other stakeholders.
Overall, AMBIC is a unique research center that is dedicated to advancing mammalian cell culture upstream development. Its collaborative approach brings together leading researchers from academia and industry to develop innovative technologies that can improve the efficiency, productivity, and quality of biomanufacturing processes. With its focus on education and workforce development, AMBIC is also helping to train the next generation of biomanufacturing professionals who will drive innovation in this important field.
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