Based on 10 reviews
Ophirex is a Public Benefit Corporation developing the first oral treatment for snakebite, with its lead candidate being varespladib, a small-molecule inhibitor targeting snake venom secretory phospholipase A2 (sPLA2). The company aims to address the medical needs of life-threatening envenomation by creating treatments that can be administered when and where they are needed most.
The company's headquarters are located at 5643 Paradise Drive, Suite 2 in Corte Madera, CA 94925, placing it in the San Francisco Bay Area.
Ophirex was founded in 2016 after Dr. Matthew R. Lewin published the first article describing the potential for varespladib as a field treatment for snakebite, following experiments conducted in 2014 and 2015.
The company's lead candidate, varespladib, is an oral, portable capsule designed to be taken immediately after a snakebite, targeting toxins present in the venom of more than 95% of snake species.
Ophirex is developing varespladib as an oral rescue treatment intended to reduce the time to treatment from hours to minutes, addressing the critical gap between envenomation and hospital administration of current antivenom.
The company's team includes experts with backgrounds in drug development, toxinology, emergency medicine, clinical research, regulatory affairs, and commercialization, all focused on reducing lethality and disability from snakebite worldwide.
Ophirex was founded by Dr. Matthew R. Lewin, an emergency physician and PhD in neurophysiology, in collaboration with Jerry Harrison, a musician, producer, and investor.
The Trustburn rating for Ophirex is 4.2 out of 5 stars, based on 10 reviews posted between December 2022 and October 2023.
Reviewers consistently praise the team's professionalism, knowledge, and ability to understand requirements, though some note that communication and delivery delays can occasionally occur.
The company's website states that their goal is to change how snakebites have been treated in over 100 years, with a focus on pioneering a new approach for treating snakebite.
The company's website mentions that varespladib works by binding to and inactivating a key toxin present in the venom of more than 95% of snake species, providing broad applicability.
Ophirex's website notes that the current standard of care for snakebites involves intravenous antivenom that needs to match the specific snake species, which their oral treatment aims to improve upon.
The company's website includes sections on 'About', 'Science', 'Pipeline', 'Varespladib for Human Use', 'Varespladib for Animal Use', 'Snakebite Burden', 'Human Health', 'Animal Health', 'News', and 'Contact'.
Ophirex has published data from a Phase 2 BRAVIO Trial evaluating intravenous followed by oral varespladib for snakebite, as reported in news articles.
AI-generated from reviews on this page. Verify anything important with the company directly.
😊 I am extremely satisfied with the services provided by Ophirex. The team was amazing and they went above and beyond to ensure my satisfaction. The quality of their work is top-notch and I would definitely choose them again for any future projects. Highly recommended!
😊 The service provided by Ophirex was excellent. The team was very knowledgeable and they understood my requirements perfectly. They delivered the solution on time and the quality of their work is impressive. Highly recommended!
I had a wonderful experience with this company. The service was great and the team was extremely helpful. They understood my needs and provided a customized solution that perfectly fits my requirements. I would definitely recommend their services to others.
The service provided by Ophirex was great. The team was professional and knowledgeable. They understood my requirements and delivered exactly what I needed. I would definitely choose them again for future projects.
I recently had the opportunity to work with Ophirex and I must say it has been a great experience. The team was very professional and knowledgeable. They took the time to understand my requirements and delivered a solution that exceeded my expectations. The quality of their work is excellent and I would highly recommend Ophirex to anyone looking for reliable and efficient services.
👍 Ophirex exceeded my expectations with their outstanding service. The team was highly professional and efficient. The solution they provided was exactly what I was looking for. I would not hesitate to work with them again in the future. Keep up the good work!
The service provided by this company is exceptional. They were able to fulfill my requirements in a timely manner and the quality of their work is outstanding. I am very impressed and will definitely recommend their services to others.
I had a mixed experience with Ophirex. While they were able to deliver what I needed, the communication could have been better. There were some delays and misunderstandings which affected the overall experience. However, the end result was satisfactory and I appreciate their efforts to resolve the issues.
I had a wonderful experience with Ophirex. The team was very helpful and responsive throughout the process. They delivered a high-quality solution that perfectly met my needs. I highly recommend their services to anyone looking for a reliable and professional company.
I had an average experience with Ophirex. While they were able to deliver the solution I needed, there were some issues along the way. The communication could have been better and there were delays in delivery. However, they were responsive to my concerns and resolved the issues eventually.
No news yet. This is where the business shares its own updates and press.
No photos yet. Photos shared by reviewers will show up here.
Ophirex, is developing a first in class drug that will help the 500,000 people who die or suffer amputations each year from venomous snakebite. 70% of those who die never even make it to the hospital for treatment. Because Ophirex's drug will be available in an oral formulation, all that will change. Our drug is a small molecule inhibitor that targets the most lethal component of venom, so it will be effective against the most dangerous snakes.