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Migralex is different from most other headache medications. First of all, it has no caffeine. Caffeine is an active ingredient in a variety of over-the-counter and prescription headache drugs. Caffeine does enhance the pain-relieving properties of other medications. However, caffeine is also responsible for causing or worsening headaches in millions of people. Almost everyone who drinks more than one or two cups of coffee a day knows that skipping their usual cup of strong morning coffee can result in a severe headache. The existence of caffeine withdrawal headaches is also well documented in scientific studies. Caffeine also causes or worsens anxiety, depression, insomnia, acid reflux, palpitations, and other problems.
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