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Dep-Xplora has invented novel prodrugs of clinically used NSAIDs (non-steroidal anti-inflammatory drugs) to be used in the development of depots for joint injection . Oral NSAIDs are widely used as rescue medicine to relieve moderate to severe postoperative pain after minor joint surgery and to alleviate inflammatory pain associated with various arthritis conditions. After injection into a joint such as the knee, the Dep-Xplora prodrug forms a depot at the site of action from which the active NSAID is released over a time period, e.g. 4-10 days.
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