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Apogee is dedicated to developing its sphingosine kinase inhibitor program for the treatment of solid tumors and a variety of chronic inflammatory diseases as well as in indications of damaging acute inflammation. Their product pipeline includes small molecule inhibitors of sphingosine kinase. Sphingosine kinase generates sphingosine-1-phosphate which drives many cancer types and inflammatory diseases and disorders. Their main disease focus is using their technologies to treat solid tumor cancers that have been validated in preclinical animal tumor models including renal cell carcinoma, breast, brain, pancreatic, myeloma and colon cancers.
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