Don't expect to see a lot of stuff other than the ...
Don't expect to see a lot of stuff other than the empty land. The 1.5 hour one way drive to the end of the Flamingo Visitor Center is TOTALLY wasting time. Only see about 10 cars in the early November. Should call them to make sure you can actually see something interesting.
The driving scenery is OK, if you are the first time to visit everglades.
It wold be much more fun and much more to see with air-boat outside the park.